EACR 2025
Lisbon, Portugal | 16th - 19th June, 2025
Bruker Spatial Biology Symposium
Expanding the Limits of Biology: Comprehensive Integrated Technologies for Multiomics in Oncology
This symposium will delve into the evolving role of multiomics research applications in oncology, focusing on how integrated approaches in spatial transcriptomics, proteomics, genomics, and bulk multiomics can advance biological understanding. Through expert discussions and real-world case studies, we will examine how fit-for-purpose multiomic solutions support discovery and translational oncology research. We will do this by featuring presentations that highlight practical applications of comprehensive multi-omic technologies in oncology research and precision medicine.
- Industry Moderator & Chair: Kevin Sheehy, Bruker Spatial Biology
- Industry-Leading Spatial Solutions for High-Plex Multiomic Tissue Exploration and Discovery: Christoph Koenig
- Streamlining Next-Gen Spatial Proteomics with EpicIF™ Technology and the PowerOMX™ Engine: Oliver Braubach
- Sub-cellular, multiomic imaging of the entire protein-coding transcriptome (18936-plex RNA) and 75-plex Protein on a single-slide FFPE tissue section using CosMx Spatial Molecular Imaging: Mirko Corselli
Speakers
Register Today!
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Poster Title |
Authors |
Poster Preview |
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Integrating single-cell spatial whole transcriptome and histopathology to uncover drivers of tumor heterogeneity in lung adenocarcinoma and squamous cell carcinoma |
Mirko Corselli, Yi Cui, Shanshan He, Michael Patrick, Megan Vandenberg, Evelyn Metzger, Stefan Rogers, Kathy Ton, Dan McGuire, Haiyan Zhai, Margaret Hoang, Michael Rhodes, Joseph Beechem |
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Bruker Beyond the Abstract | Gather at our booth for informal technology highlights
Join us the Bruker Spatial Biology Booth during the three times daily break sessions (morning, lunch and afternoon) for an informal highlight on each the our Spatial Biology Platforms - CosMx® Spatial Molecular Imager, CellScape™ Precise Spatial Proteomics Platform and GeoMx® Digital Spatial Profiler.
See us at Booth #54-55
CosMx Highlight
Mapping the spatial whole transcriptome from normal to tumor tissue in renal clear cell carcinoma: Tumorigenesis and microenvironmental shifts at single-cell resolution
CellScape Highlight
Development of a multi-omic spatial phenotyping assay for affirmative detection of CAR-T cells in the tumor immune microenvironment of solid pediatric tumors.
GeoMx Highlight
Advancing high-plex spatial multiomics: Integration of a novel 1,000+ plex Discovery Proteome Atlas with an
18,000+ Whole Transcriptome Atlas to investigate multiple cancer pathologies
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Visit our posters at EACR!
Find us at the poster session on June 17th and 18th
Integrating single-cell spatial whole transcriptome and histopathology to uncover drivers of tumor heterogeneity in lung adenocarcinoma and squamous cell carcinoma (EACR25-3043)
Christoph Konig, Michael Patrick, Shanshan He, Liang Zhang, Patrick Danaher, Sierra Mckinzie, Haiyan Zhai, Michael Rhodes, Joseph Beechem
Innovative multiomic spatial biology assay for comprehensive immune characterization of the tumor microenvironment (EACR25-1934)
Jannik Boog, Arne Christians, Daniel Jimenez Sanchez, Sara Bodbin, Agata Wicher, Subham Basu, Randy Chen, Aneesh Acharya, Hong Liang, Shruti Shridar, Michelle Poon, Tan Char Loo, Ng Siok Bian, Anand Jeyasekharan, Oliver Braubach
Enhanced photobleaching for fast and highly multiplexed immunofluorescence staining with broad reagent and assay compatibility (EACR25-1997)
Thore Böttke, Arne Christians, Marcus Böttcher, Jannik Boog, Julia Feldhaus, Anke Brix, Daniel Jimenez Sanchez, Oliver Braubach
CosMx®SMI Spatially Resolved Whole Transcriptome in FFPE Tissue –A Paradigm Shift for Tissue Analysis (EACR25-3042)
Mirko Corselli, Yi Cui, Shanshan He, Michael Patrick, Megan Vandenberg, Evelyn Metzger, Stefan Rogers, Kathy Ton, Dan McGuire, Haiyan Zhai, Margaret Hoang, Michael Rhodes, Joseph Beechem
Enhanced Spatial Proteomics: High-precision analysis of the tumor microenvironment (EACR25-1927)
Jonah Rauer, Matthew H. Ingalls, J Spencer Schwarz, Charles E. Jackson, Jannik Boog, Arne Christians, Kayla E Cashion, Adam Northcutt, Anke Brix, Oliver Braubach
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Bonus Presentation: Whole transcriptome spatial molecular imaging in matched pre and post treatment specimens to identify therapeutic vulnerabilities and treatment-associated effects in pancreatic
Dr. Will Hwang shared his data at the most recent AACR event and we will re-air his presentation for you here. This research highlights new strategies for analyzing whole-transcriptome spatial transcriptomics at subcellular resolution and the potential thereof to identify novel treatment-associated effects. You won’t want to miss it.
Presenter: Will Hwang, MD, PhD Assistant Professor, Harvard Medical School; Principal Investigator, Massachusetts General Hospital; Associate Faculty Member, Broad Institute of MIT and Harvard
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