ON-DEMAND WEBINAR
Advancing T Cell Therapy Discovery and Translation Using Real-time Single-Cell Functional Biology
Developing the next generation of cell-based therapies requires technologies capable of linking phenotype, function, and biology at the single-cell level in real time. In this webinar, Dr. Anthony Zamora will discuss how real-time single-cell functional biology workflows on the Beacon® Optofluidic platform can be used to accelerate discovery and translational efforts for engineered T-cell therapies, including TCR T and CAR T cells. Attendees will gain insight into how multiplexed single-cell analysis approaches can help uncover functional heterogeneity, characterize therapeutic potency and efficacy, and identify biological features associated with improved antitumor specificity and efficacy.
This webinar will highlight how integrated single-cell workflows can support neoantigen and TCR discovery, evaluate functional responses of engineered T cells, and reveal how experimental variables may influence CAR T-cell phenotype and function. This session will further demonstrate how combining dynamic functional, cellular, and transcriptional readouts can help uncover mechanistic differences between therapeutic modalities.
Attendees will learn how to:
- Apply real-time single-cell functional analysis to TCR T and CAR T-cell research
- Use multimodal readouts to interrogate engineered T-cell biology
- Characterize functional heterogeneity in different types of cell-based therapies
- Leverage single-cell workflows to accelerate translational T-cell therapy discovery and development
Speakers
Anthony E. Zamora, Ph.D.
Associate Professor, Internal Medicine Division of Malignant Hematology/Cellular Therapy and Transplantation University of California, Davis |
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Dr. Zamora is an Associate Professor at the Department of Internal Medicine (Hematology and Oncology) at University of California, Davis. He specializes in cancer immunology and is focused on developing next-generation immunotherapies that enable the immune system to more precisely and effectively eliminate cancer cells. Dr. Zamora's work uses cellular engineering to enhance immune cell specificity while reducing off-target toxicities, and integrates advanced single-cell technologies to profile the phenotype, function, and receptor repertoires of neoantigen-specific T cells. He obtained his PhD in Immunology from University of California, Davis.
ON-DEMAND | STREAM NOW
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